ProSci

MEK1/2 Antibody

Product Code:
 
PSI-79-648
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of extract from HeLa and JK cells using MEK1/2 Antibody #21428
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Western blot analysis of extract from HeLa and JK cells using MEK1/2 Antibody #21428

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PSI-79-648-0.1mg0.1mg£481.00
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Further Information

Additional Names:
CFC3, MEK1, MKK1, MAPKK1, PRKMK1
Application Note:
Western Blot: 1:500~1:1000
Background:
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
Background References:
  • Seger R., Seger D., Lozeman F. J., Ahn N. G., Graves L. M., Campbell J. S., Ericsson L., Harrylock M., Jensen A. M., Krebs E. G. J. Biol. Chem. 267:25628-25631 (1992) Mukherjee S., Keitany G., Li Y., Wang Y., Ball H. L., Goldsmith E. J., Orth K. Science 312:1211-1214 (2006)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
MEK1/2 antibody was raised against a peptide sequence around aa.235-239 (L-Q-G-T-H) derived from Human MEK1/2.
NCBI Gene ID #:
5604
NCBI Official Name:
mitogen-activated protein kinase kinase 1
NCBI Official Symbol:
MAP2K1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
NP_002746.1
Protein GI Number:
5579478
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total MEK1/2 protein.
Swissprot #:
Q02750