Further Information
PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1
PABPC1 antibody can be used for detection of PABPC1 by ELISA at 1:1562500. PABPC1 antibody can be used for detection of PABPC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
The poly (A)-binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly (A)-binding protein (PABP), which is found complexed to the 3-prime poly (A) tail of eukaryotic mRNA, is required for poly (A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.
- Rivera, C.I. (2008) Virology 375 (1), 59-72.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PABPC1.
26986
poly(A) binding protein, cytoplasmic 1
PABPC1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
NP_002559
46367787
Antibody is purified by peptide affinity chromatography method.
RNA Binding ,Cancer
P11940
Optimal dilutions for each application to be determined by the researcher.