Sciencell

Mouse Pulmonary Fibroblasts from C57BL/6

Product Code:
 
SC-M3300-57
Product Group:
 
Primary Cells
Supplier:
 
Sciencell
Host Type:
 
Mouse
Regulatory Status:
 
RUO
1 / 1

No additional charges, what you see is what you pay! *

CodeSizePrice
SC-M3300-575 x 10^5 cells/vial£505.00
Quantity:
Prices exclude any Taxes / VAT
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Extra Description:
MPF from ScienCell Research Laboratories are isolated from C57BL/6 mouse lung. MPF are cryopreserved at passage one and delivered frozen.. Each vial contains >5 x 10^5 cells in 1 ml volume.
Long Description:
The most abundant cell type in the lung interstitium is the fibroblast. Pulmonary fibroblasts (PF) exhibit typical fibroblast morphology, however, they also possess some distinguishing features such as long, branching processes and gap junctions. PF function to produce type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa. PF also play an important role in the repair and remodeling processes following tissue damage. The controlled accumulation of fibroblasts to sites of inflammation is crucial to effective tissue repair after injury. An inadequate or an excessive accumulation of fibroblasts results in abnormal tissue function and can lead to the development of pulmonary fibrosis. Notably, pulmonary fibrosis has been observed in acute COVID-19 patients, however, little is known about how the fibrosis will affect lung function in recovered patients. The culture of mouse PF (MPF) in vitrocan be used to further elucidate the mechanisms of pulmonary fibrosis and other types of lung disorders. MPF from ScienCell Research Laboratories are isolated from C57BL/6 mouse lung. MPF are cryopreserved at passage one and delivered frozen. Each vial contains >5 x 10^5 cells in 1 ml volume. MPF are characterized by immunofluorescence with antibody specific to fibronectin. MPF are negative for mycoplasma, bacteria, yeast, and fungi. MPF are guaranteed to further expand for 5 population doublings under the conditions provided by ScienCell Research Laboratories. Recommended Medium - It is recommended to use Fibroblast Medium (FM, Cat. #2301) for culturing MPFin vitro.