AdipoGen Life Sciences

n-Octyl-beta-D-thioglucopyranoside (high purity)

Product Code:
 
AG-CC1-0005
Product Group:
 
Detergents
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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AG-CC1-0005-G0011 g£60.00
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AG-CC1-0005-G0055 g£210.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
OTG; Octylthioglucoside; n-Octyl 1-thio-beta-D-glucopyranoside
Appearance:
White powder.
CAS:
85618-21-9
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Hygroscopic.Protect from light and moisture.
InChi:
InChI=1S/C14H28O5S/c1-2-3-4-5-6-7-8-20-14-13(18)12(17)11(16)10(9-15)19-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14+/m1/s1
InChiKey:
CGVLVOOFCGWBCS-RGDJUOJXSA-N
Long Description:
Chemical. CAS: 85618-21-9. Formula: C14H28O5S. MW: 308.4. Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes. For the stabilization and activation of enzymes. Used for cell lysis experiments.
MDL:
MFCD00012189
Molecular Formula:
C14H28O5S
Molecular Weight:
308.4
Package Type:
Vial
Product Description:
Non-ionic detergent. For functional solubilization, purification and crystallography of membrane proteins. The thioether linkage makes it resistant to degradation by beta-glucosidase enzymes. For the stabilization and activation of enzymes. Used for cell lysis experiments.
Purity:
>99% (HPLC) | [alpha-Isomer <0.01% (HPLC)] | [n-Octanthiol <0.001% (HPLC)]
SMILES:
CCCCCCCCSC1OC(CO)C(O)C(O)C1O
Solubility Chemicals:
Soluble in water or methanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.

References

Use of n-octyl-beta-D-thioglucoside, a new nonionic detergent, for solubilization and reconstitution of membrane proteins: T. Tsuchiya & S. Saito; J. Biochem. 96, 1593 (1984) | Characteristics of n-octyl beta-D-thioglucopyranoside, a new non-ionic detergent useful for membrane biochemistry: S. Saito & T. Tsuchiya; Biochem. J. 222, 829 (1984) | Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins: M. Chami, et al.; J. Struct. Biol. 133, 64 (2001) | Surface Activity, Micelle Formation, and Growth of n-Octyl-beta-d-Thioglucopyranoside in Aqueous Solutions at Different Temperatures: J.A. Molina-Bolivar, et al.; J. Phys. Chem. B 108, 12813 (2004) | Use of n-Octyl-beta-D-thioglucopyranoside in the isolation of a bacterial membrane protein: an improved method for immunological applications.: J.M. Peula-Garcia, et al.; J. Surface Sci. Technol. 22, 141 (2006) | Development and crystallization of a minimal thermostabilised G protein-coupled receptor: T. Warne, et al.; Protein Expr. Purif. 65, 204 (2009) | Solubilization and structural stability of bacteriorhodopsin with a mild nonionic detergent, n-Octyl-beta-thioglucoside: A. Asada, & M. Sonoyama; Biosci. Biotechnol. Biochem. 75, 376 (2011) | Characterization of mixed non-ionic surfactants n-octyl-beta-D-thioglucoside and octaethylene-glycol monododecyl ether: micellization and microstructure: C.C. Ruiz & J.A. Molina-Bolivar; J. Colloid. Interface Sci. 361, 178 (2011) | Mass spectrometry of intact membrane protein complexes: A. Laganowsky, et al.; Nat. Protocols 8, 639 (2013)