Sciencell

Puromycin

Product Code:
 
SC-0543
Supplier:
 
Sciencell
Regulatory Status:
 
RUO
Shipping:
 
Dry Ice
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CodeSizePrice
SC-054310 mg/ml; 10 x 1 ml£283.00
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Further Information

Description:
Puromycin is an aminonucleoside antibiotic isolated from Streptomyces alboniger. Puromycin terminates protein synthesis at the level of translation in prokaryotic and eukaryotic cells and is active against gram-positive bacteria and weakly active against gram-negative bacteria. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase (pac) gene [1, 2]. Exogenous expression of the pac gene is commonly used in conjunction with puromycin to generate stable cell lines. Most working concentrations range from 1-10 ml; however, the optimal concentration should be determined for individual cell types and culture conditions. In most cases, puromycin kills 99% of non-resistant cells within 48 hours.
Extra Description:
PURO-10 is for research use only. It is not approved for human or animal use, or for application in clinical or in vitro diagnostic procedures.

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