ProSci

KLF4-TAT Recombinant Protein

Product Code:
 
PSI-40-524
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized KLF4-TAT recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted KLF4-TAT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein,
 

No additional charges, what you see is what you pay! *

CodeSizePrice
PSI-40-524-0.005mg0.005mg£300.00
Quantity:
PSI-40-524-0.025mg0.025mg£428.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 14-21 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • Show All

Further Information

Additional Names:
EZF, GKLF, EZF, Krueppel-like factor 4, Epithelial zinc finger protein EZF
Background:
KLF4 is a member of the Kruppel-like factor (KLF) family of zinc finger transcription factors. Members of this family have in common 3 contiguous C2H2-type zinc fingers at the carboxyl terminus that comprise the DNA-binding domain. KLF4 is highly expressed in skin and gut epithelial tissues, but is also found in various other cells and tissues, including vascular endothelial cells, lymphocytes, lung, and testis. It is an important regulator of the cell cycle, transcription, and cell differentiation. Together with Sox2, Oct4, and cMyc, KLF4 can induce the reprogramming of primary human fibroblasts to a pluripotent state. KLF4 and other transcription factors can be introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors into primary as well as transformed cells. Recombinant Human KLF4-TAT is a 483 amino acid protein, including a 13-residue C-terminal TAT peptide, with a calculated molecular weight of 51.7kDa. Recombinant Human KLF4-TAT is a mixture of the expected sequence beginning at Met1 and a truncated isoform beginning at Tyr54. Due to post-translational modifications, SDS-PAGE gel shows bands at approximately 72 and 66kDa, under reduced conditions.
Biological Activity:
Endotoxin level is less than 0.1 ng per ug (1EU/μg).
NCBI Gene ID #:
9314
NCBI Official Name:
Kruppel-like factor 4 (gut)
NCBI Official Symbol:
KLF4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_004226.3
Protein GI Number:
194248077
Purity:
Greater than 90% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
O43474

Documents