ProSci

CD21 Antibody [HB5] (FITC)

Product Code:
 
PSI-76-154
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HB5
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-154-100tests100tests£536.00
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Further Information

Additional Names:
CR, C3DR, CD21, CVID7, SLEB9, CR2
Background:
The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein. CD21 is reported to be involved in B cell activation and proliferation. It is expressed on follicular dendritic cells, mature B cells, a subset of T cells, and a subset of epithelial cells. It is the receptor utilized by the Epstein-Barr virus to infect B cells.
Background References:
  • Tedder, T. F., Clement, L. T., Cooper, M. D. (1984). Expression of C3d receptors during human B cell differentiation: immunofluorescence analysis with the HB-5 monoclonal antibody.The Journal of Immunology,133(2), 678-683.
  • Fingeroth, J. D., Weis, J. J., Tedder, T. F., Strominger, J. L., Biro, P. A., Fearon, D. T. (1984). Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2.Proceedings of the National Academy of Sciences,81(14), 4510-4514.
  • Nemerow, G. R., Wolfert, R. O. B. E. R. T., McNaughton, M. E., Cooper, N. R. (1985). Identification and characterization of the Epstein-Barr virus receptor on human B lymphocytes and its relationship to the C3d complement receptor (CR2).Journal of virology,55(2), 347-351.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
1380
NCBI Official Name:
complement component (3d/Epstein Barr virus) receptor 2
NCBI Official Symbol:
CR2
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The HB5 monoclonal antibody specifically reacts with human CD21, a 145 kDA glycosylated type I integral membrane protein.
Swissprot #:
P20023
User NOte:
Optimal dilutions for each application to be determined by the researcher.