ProSci

CD20 Antibody [2H7] (PE)

Product Code:
 
PSI-76-006
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
2H7
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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PSI-76-006-100tests100tests£536.00
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Further Information

Additional Names:
B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1
Background:
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
Background References:
  • Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
  • Polyak, M. J., Deans, J. P. (2002). Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes
  • Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
931
NCBI Official Name:
membrane-spanning 4-domains, subfamily A, member 1
NCBI Official Symbol:
MS4A1
NCBI Organism:
Homo sapiens
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Immunology
SPECIFICITY:
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule.
Swissprot #:
P11836
User NOte:
Optimal dilutions for each application to be determined by the researcher.