TNF-Alpha Antibody [MAb11]
Antibody Isotype:
Mouse IgG1, kappa
Antibody Clonality:
Monoclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Flow Cytometry
- Immunohistochemistry (IHC)
Storage:
The product should be stored undiluted at 4°C. Do not freeze.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
DIF, TNFA, TNFSF2, TNF-alpha, TNF
The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha (TNF-alpha), a 157 amino acid non-glycosylated protein. TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. The MAB11 antibody was generated from recombinant human TNF and is reported to be a neutralizing antibody.
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
7124
tumor necrosis factor
TNF
Homo sapiens
liquid
The monoclonal antibody was purified utilizing affinity chromatography.
Innate Immunity,Chemokines & Cytokines, Growth Factors,Apoptosis
The MAb11 monoclonal antibody specifically reacts with human tumor necrosis factor alpha (TNF-alpha), a 157 amino acid non-glycosylated protein.
P01375
Optimal dilutions for each application to be determined by the researcher.