ProSci

CD282 Antibody [mT2.7] (FITC)

Product Code:
 
PSI-76-951
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
mT2.7
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-76-951-0.025mg0.025mg£373.00
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Further Information

Additional Names:
Ly105, Tlr2
Background:
The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2). It is a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. CD282 is expressed on monocytes, macrophages, dendritic cells, and the RAW264.7 cell line and is involved distinguishing bacterial lipoproteins.
Background References:
  • Mechetner, E. B., Roninson, I. B. (1992). Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.Proceedings of the National Academy of Sciences,89(13), 5824-5828.
  • Chaudhary, P. M., Mechetner, E. B., Roninson, I. B. (1992). Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments].Blood,80(11), 2735-2739.
  • Goda, K., Fenyvesi, F., Bacs, Z., Nagy, H., Mrin, T., Megyeri, A., ... Szab, G. (2007). Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody.Journal of Pharmacology and Experimental Therapeutics,320(1), 81-88.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
FITC
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
24088
NCBI Official Name:
toll-like receptor 2
NCBI Official Symbol:
Tlr2
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Innate Immunity
SPECIFICITY:
The mT2.7 monoclonal antibody specifically reacts with mouse CD282, the Toll-like receptor 2 (TLR2).
Swissprot #:
Q9QUN7
User NOte:
Optimal dilutions for each application to be determined by the researcher.