Further Information
B7, B70, MB7, B7-2, B7.2, CLS1, Ly58, ETC-1, Ly-58, MB7-2, Cd28l2, TS/A-2, Cd86
The PO3.1 monoclonal antibody specifically reacts with CD86, also known as B7-2, a surface 80 kDa receptor and member of the B7 family. CD86 is a costimulatory molecule, expressed on B and T cells, dendritic cells, astrocytes, macrophages, Langerhans cells, and at a low level in newly explanted B and T lymphocytes. CD86 expression on B lymphocytes is upregulated by B-Cell Receptor complex, CD40 and certain cytokine receptors. CD80 (B7-1) and CD 86 (B7-2) are receptors for CD28 and CTLA-4, on the surface of T lymphocytes, enhancing the interactions between B and T cells.
- McMichael, A. J. (1987).Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA.
- Lankester, A. C., van Schijndel, G. M., Cordell, J. L., van Noesel, C. J., van Lier, R. A. (1994). CD5 is associated with the human B cell antigen receptor complex.European journal of immunology,24(4), 812-816.
- Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009). A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57(12), 1159-1167.
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
batch dependent
PE
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
12524
CD86 antigen
Cd86
Mus musculus
liquid
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Innate Immunity
The PO3.1 monoclonal antibody specifically reacts with CD86, also known as B7-2, a surface 80 kDa receptor and member of the B7 family.
P42082
Optimal dilutions for each application to be determined by the researcher.