anti-IL-36beta (human) mAb (Jacky-1)
Product Code:
AG-20B-0069
Antibody Isotype:
Mouse IgG1κ
Antibody Clonality:
Monoclonal
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
Alternate Names/Synonyms:
Interleukin-36beta Interleukin-1 Family Member 8; IL-1F8
1mg/ml
32160000
liquid
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Recombinant human IL-36beta.
Monoclonal Antibody. Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma. Isotype: Mouse IgG1kappa. Clone: Jacky-1. Applications: ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
Plastic Vial
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
>95% (SDS-PAGE)
Purified from concentrated hybridoma tissue culture supernatant.
Recognizes human IL-36beta. Does not cross-react with mouse IL-36beta and IL-36gamma.
Non-hazardous
Primary Antibodies
12352203
Stable for at least 1 year after receipt when stored at -20°C.