ProSci

Bmf Antibody [9G10]

Product Code:
 
PSI-36-173
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
9G10
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C.
 

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PSI-36-173-100ug100ug£638.00
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Further Information

Additional Names:
Bcl-2-modifying Factor
Application Note:
Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml).
Background:
Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
Buffer:
Liquid. In PBS containing 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant mouse Bmf.
NCBI Gene ID #:
90427
NCBI Official Name:
Bcl2 modifying factor
NCBI Official Symbol:
BMF
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
15723378
Protein GI Number:
NP_277038
Purification:
>95% (SDS-PAGE)
Research Area:
Apoptosis,Cancer,Immunology
SPECIFICITY:
Recognizes human and mouse Bmf. Detects several cross-reactivity bands of unknown identity in mice by western blot.
Swissprot #:
Q96LC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.