ProSci

Nampt Recombinant Protein

Product Code:
 
PSI-90-053
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Rat
Storage:
 
Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-053-50ug50ug£765.00
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Further Information

Additional Names:
Pre-B Cell Colony Enhancing Factor 1, PBEF1, Nicotinamide Phosphoribosyltransferase
Application Note:
This recombinant proteins is for research use only.
Background:
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Buffer:
0.2um-filtered solution in PBS, pH 7.2.
Concentration:
0.35mg/ml
Fusion Tag:
DDDDK Tag
NCBI Gene ID #:
297508
NCBI Official Name:
nicotinamide phosphoribosyltransferase
NCBI Official Symbol:
Nampt
NCBI Organism:
Rattus norvegicus
Physical State:
Liquid
Protein Accession #:
Q80Z29
Protein GI Number:
68565643
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P04916

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