Sciencell

GeneQuery™ Human T Cell Receptor Signaling Pathway qPCR Array Kit

Product Code:
 
SC-GK021
Product Group:
 
PCR Kits
Supplier:
 
Sciencell
Host Type:
 
Human
Regulatory Status:
 
RUO
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SC-GK0211 kit£297.00
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Further Information

Description:
ScienCell's GeneQuery™ Human T Cell Receptor Signaling Pathway qPCR Array Kit (GQH-TRS) is designed to facilitate gene expression profiling of 88 key genes involved in T cell receptor signaling pathway. Brief examples of how included genes may be grouped according to their functions are shown below:
  • T cell receptor complex components: - CD3D, CD3E, CD3G
  • Co-receptors: - CD4, CD8A, CD8B
  • Co-inhibitors: - PDCD1, CTLA4
  • Co-stimulators: - ICOS, CD28
  • Kinases: - FYN, ZAP70
  • MAPK pathway: - KRAS, HRAS, NRAS, RAF1, MAP2K1, MAPK1, MAPK3
  • PI3K/AKT pathway: - PI3Ks, AKT1, AKT2
  • IKK/NFKB pathway: - NFKBs, DAG1, BCL10, CARD11, MAP3K7, MALT1, CHUK, IKBKB, IKBKG
GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg^2+ , and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis.
Extra Description:
This kit is designed to facilitate gene expression profiling of 88 key genes involved in T cell receptor signaling pathway.