ProSci

Lumican Recombinant Protein

Product Code:
 
PSI-91-343
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-91-343-0.05mg0.05mg£560.00
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Further Information

Additional Names:
Lumican, Keratan Sulfate Proteoglycan Lumican, KSPG Lumican, LUM, LDC, SLRR2D
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.
Buffer:
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
4060
NCBI Official Name:
lumican
NCBI Official Symbol:
LUM
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
37.7 kD
Protein Accession #:
P51884
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P51884

Documents