Thimet Oligopeptidase Recombinant Protein

Product Code:

PSI-91-159

Product Group:

Recombinant Proteins

Supplier:

ProSci

Regulatory Status:

RUO

Target Species:

Human

Storage:

Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

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Code	Size	Price

PSI-91-159-0.05mg

0.05mg

£883.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Additional Names:

Thimet Oligopeptidase, Endopeptidase 24.15, MP78, THOP1

Application Note:

This recombinant protein can be used for biological assays. For research use only.

Background:

Thimet Oligopeptidase (THOP1) belongs to the peptidase M3 family which includes neurolysin and mitochondrial intermediate peptidase. THOP1 is located in Cytoplasm. THOP1 is widely expressed in human tissues and can detected in different subcellular locations. THOP1 is preferential cleavage for bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues. THOP1 is involved in the metabolism of neuropeptides under 20 amino acid residues and degradation of cytoplasmic peptide. In addition, THOP1 also can degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.

Buffer:

Supplied as a 0.2 um filtered solution of 20mM PB, 100mM NaCl, 10% Glycerol, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Fusion Tag:

C-6 His tag

NCBI Gene ID #:

7064

NCBI Official Name:

thimet oligopeptidase 1

NCBI Official Symbol:

THOP1

NCBI Organism:

Homo sapiens

Physical State:

Liquid

Predicted Molecular Weight:

80 kD

Protein Accession #:

P52888

Purity:

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

Recombinant Protein Sequence:

Thr32-Gly402

Source:

E. coli

Swissprot #:

P52888

Documents

Datasheet