ProSci

PI4KB Recombinant Protein

Product Code:
 
PSI-91-682
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-682-0.05mg0.05mg£883.00
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This product comes from: United States.
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Further Information

Additional Names:
Phosphatidylinositol 4-Kinase Beta, PI4K-Beta, PI4KBeta, PtdIns 4-Kinase Beta, NPIK, PI4K92, PI4KB, PIK4CB
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Phosphatidylinositol 4-Kinase beta (PI4KB) belongs to the PI3/PI4-kinase family and Type III PI4K subfamily. PI4KB contains one PI3K/PI4K domain and one PIK helical domain. It is highly expressed in heart, skeletal muscle, pancreas, testis and ovary,; it is lowly expressed in liver tissue. PI4KB kinase activity can be inhibited by wortmannin, and increased by interacting with NCS1/FREQ. PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). In addition, PI4KB may regulate Golgi disintegration/reorganization during mitosis.
Buffer:
Supplied as a 0.2 um filtered solution of 25mM Tris.HCl,pH7.3,100mM glycine,10%glycerol. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
5298
NCBI Official Name:
phosphatidylinositol 4-kinase beta
NCBI Official Symbol:
PI4KB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
90.8 kD
Protein Accession #:
Q9UBF8-2
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q9UBF8-2

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