Further Information
Alternate Names/Synonyms:
PVR; Polio Virus Receptor; Necl-5
1mg/ml
32160000
liquid
50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Do not freeze.Protect from light.
Recombinant human CD155.
R-PE
Monoclonal Antibody. Isotype: Mouse IgG1kappa. Clone: ANC2B2. Applications: ELISA, FACS. 50mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3. Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.
Plastic Vial
Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.
>95% (SDS-PAGE)
Purified from concentrated hybridoma tissue culture supernatant.
Binds to human cell surface CD155 on U-937 cells, and binds to recombinant human CD155 in EIA.
Non-hazardous
Primary Antibody Conjugates
12352203
Stable for at least 1 year after receipt when stored at +4°C.