ScienCell's GeneQuery™ Human Neuronal Cell Biology qPCR Array (GQH-NEU) profiles 88 key genes involved in normal neuron function. Neurons are responsible for processing and transmitting information throughout the body via electric potentials. They are a core component of the central nervous system and specialized neurons are key elements of the sensory and motor units. Below are brief examples of how included genes may be grouped according to their function in neuronal cell biology:
- Neurotransmission: - ABAT, GABRB1, GRM3, SLC32A1, VAMP2
- Axonal guidance: - EFNA2, ROBO1, NTN1, NRP1, SLIT1
- Synapse formation and maintenance: - DLG2, NLGN3, SYN1, SYP, DLG4
- Neurite outgrowth: - GLDN, GPRIN1, NRCAM, RTN4, SEMA3G
- Differentiation: - BMP2, EVX1, GNL3, SMARCA4, PROM1
Note: - all gene names follow their official symbols by the Human Genome Organization Gene Nomenclature Committee (HGNC).
GeneQuery™ qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg^2+ , and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis.
This array kit profiles 88 key genes involved involved in normal neuron function. Neurons are responsible for processing and transmitting information throughout the body via electric potentials.
