Chemodex

D-Aspartic acid

Product Code:
 
CDX-A0326
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short Term: +20°C. Long Term: +20°C
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Chemical Structure
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Chemical Structure

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CDX-A0326-G02525 g£59.00
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CDX-A0326-G100100 g£145.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
H-D-Asp-OH; D-Aspartate; D-Asp; (R)-(-)-Aminosuccinic acid; (R)-2-Aminosuccinic acid; D-Aminosuccinic acid
Appearance:
White to off-white powder.
CAS:
1783-96-6
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m1/s1
InChiKey:
CKLJMWTZIZZHCS-UWTATZPHSA-N
Long Description:
Chemical. CAS: 1783-96-6. Formula: C4H7NO4. MW: 133.1. Synthetic. Endogenous NMDA receptor agonist with similar activity to the L-isomer. Endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. Acts as a neurotransmitter/neuromodulator. Increases cAMP in neuronal cells and is transported from the synaptic clefts to presynaptic nerve cells through a specific transporter. In the endocrine system, D-Asp is involved in the regulation of hormone synthesis and release. Enhances gonadotropin-releasing hormone (GnRH) release and induces oxytocin and vasopressin mRNA synthesis in rats. In the pituitary gland, it stimulates the secretion of the hormones prolactin (PRL), luteinizing hormone (LH) and growth hormone (GH). Also involved in testosterone and progesterone release.
MDL:
MFCD00063081
Molecular Formula:
C4H7NO4
Molecular Weight:
133.1
Package Type:
Vial
Product Description:
Endogenous NMDA receptor agonist with similar activity to the L-isomer. Endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. Acts as a neurotransmitter/neuromodulator. Increases cAMP in neuronal cells and is transported from the synaptic clefts to presynaptic nerve cells through a specific transporter. In the endocrine system, D-Asp is involved in the regulation of hormone synthesis and release. Enhances gonadotropin-releasing hormone (GnRH) release and induces oxytocin and vasopressin mRNA synthesis in rats. In the pituitary gland, it stimulates the secretion of the hormones prolactin (PRL), luteinizing hormone (LH) and growth hormone (GH). Also involved in testosterone and progesterone release.
Purity:
>99% (Titration)
SMILES:
O=C(O)[C@H](N)CC(O)=O
Solubility Chemicals:
Soluble in 1N ammonium hydroxide (100 mg/ml). Slightly soluble in water.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

References

(1) H.J. Olverman, et al.; Neuroscience 26, 17 (1988) | (2) S. Ishio, et al; Neurosci. Lett. 249, 143 (1998) | (3) G. D'Aniello, et al.; Endocrinol. 141, 3862 (2000) | (4) A. D'Aniello; Brain Res. Rev. 53, 215 (2007) (Review) | (5) E. Topo, et al.; Reprod. Biol. Endocrinol. 7, 120 (2009) | (6) E. Topo, et al.; Amino Acids 38, 1561 (2010) | (7) S. D'Aniello, et al.; FASEB J. 25, 1014 (2011)