Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Targeting protein for Xklp2, Differentially expressed in cancerous and non-cancerous lung cells 2, DIL-2, Hepatocellular carcinoma-associated antigen 519, Hepatocellular carcinoma-associated antigen 90, Protein fls353, Restricted expression proliferation-associated protein 100, p100, TPX2, C20orf1, C20orf2, DIL2, HCA519
For WB starting dilution is: 1:1000
TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
- Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
- Bibby, R.A., et al. J. Biol. Chem. 284(48):33177-33184(2009)
- Shigeishi, H., et al. Int. J. Oncol. 34(6):1565-1571(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine
This TPX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human TPX2.
22974
Targeting protein for Xklp2
TPX2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Q9ULW0
13124096
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle
Q9ULW0
Optimal dilutions for each application to be determined by the researcher.