Further Information
Alkaline phosphatase, placental type, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1, ALPP, PLAP
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
There are at least four distinct but related alkaline
phosphatases: intestinal, placental, placental-like, and
liver/bone/kidney (tissue non-specific). The first three are
located together on chromosome 2 while the tissue non-specific form
is located on chromosome 1. The product of this gene is a membrane
bound glycosylated enzyme, also referred to as the heat stable
form, that is expressed primarily in the placenta although it is
closely related to the intestinal form of the enzyme as well as to
the placental-like form. The coding sequence for this form of
alkaline phosphatase is unique in that the 3' untranslated region
contains multiple copies of an Alu family repeat. In addition, this
gene is polymorphic and three common alleles (type 1, type 2 and
type 3) for this form of alkaline phosphatase have been well
characterized.
- Stec, B., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 8), 866-870 (2010) :
- Wang, F., et al. Am. J. Surg. Pathol. 33(10):1529-1539(2009)
- Estrada, K., et al. Hum. Mol. Genet. 18(18):3516-3524(2009)
- Zhu, J.F., et al. Zhonghua Wai Ke Za Zhi 47(5):381-384(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This ALPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.
250
Alkaline phosphatase, placental type
ALPP
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
P05187
130737
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Immunology
P05187
Optimal dilutions for each application to be determined by the researcher.