Further Information
Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29, ITGB1, FNRB, MDF2, MSK12
For WB starting dilution is: 1:1000
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
- Martchenko, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15583-15588(2010) Caicedo-Carvajal, C.E., et al. PLoS ONE(7), E11830 (2010)Rikova, K., et al. Cell 131(6):1190-1203(2007) Seales, E.C., et al. J. Biol. Chem. 280(45):37610-37615(2005) Armulik, A. Front. Biosci. 7, D219-D227 (2002) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Pig, Chicken, Xenopus, Bovine
This ITGB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 759-785 amino acids from the C-terminal region of human ITGB1.
3688
Integrin beta-1
ITGB1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
P05556
218563324
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Immunology,Neuroscience,Signal Transduction
P05556
Optimal dilutions for each application to be determined by the researcher.