Further Information
Mast/stem cell growth factor receptor Kit, SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, CD117, KIT, SCFR
For WB starting dilution is: 1:1000
This gene encodes the human homolog of the proto-oncogene
c-kit. C-kit was first identified as the cellular homolog of the
feline sarcoma viral oncogene v-kit. This protein is a type 3
transmembrane receptor for MGF (mast cell growth factor, also known
as stem cell factor). Mutations in this gene are associated with
gastrointestinal stromal tumors, mast cell disease, acute
myelogenous lukemia, and piebaldism. Multiple transcript variants
encoding different isoforms have been found for this gene.
- Molderings, G.J., et al. Immunogenetics 62 (11-12), 721-727 (2010) :
- Cheng, M., et al. Circ. Res. 107(9):1083-1093(2010)
- Chi, P., et al. Nature 467(7317):849-853(2010)
- Rossi, S., et al. Am. J. Surg. Pathol. 34(10):1480-1491(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Xenopus
This KIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-577 amino acids from the Central region of human KIT.
3815
Mast/stem cell growth factor receptor Kit
KIT
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
P10721
125472
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Immunology,Neuroscience,Signal Transduction
P10721
Optimal dilutions for each application to be determined by the researcher.