Further Information
Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAPK1, ERK2, PRKM1, PRKM2
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
ERK2 is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
- Grey, A., et al., Endocrinology 144(11):4886-4893 (2003).
- Sawafuji, K., et al., Am. J. Hematol. 72(1):67-69 (2003).
- Liao, Y., et al., Mol. Cell. Biol. 23(19):6836-6848 (2003).
- Garcia-Lora, A., et al., Cancer Immunol. Immunother. 52(1):59-64 (2003).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine
This MAPK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-285 amino acids from the C-terminal region of human MAPK1.
5594
Mitogen-activated protein kinase 1
MAPK1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
P28482
119554
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cancer,Cell Cycle,Immunology,Obesity,Neuroscience,Signal Transduction
P28482
Optimal dilutions for each application to be determined by the researcher.