Further Information
Potassium voltage-gated channel subfamily A member 5, HPCN1, Voltage-gated potassium channel HK2, Voltage-gated potassium channel subunit Kv15, KCNA5
For WB starting dilution is: 1:1000
Potassium channels represent the most complex class of
voltage-gated ino channels from both functional and structural
standpoints. Their diverse functions include regulating
neurotransmitter release, heart rate, insulin secretion, neuronal
excitability, epithelial electrolyte transport, smooth muscle
contraction, and cell volume. Four sequence-related potassium
channel genes - shaker, shaw, shab, and shal - have been identified
in Drosophila, and each has been shown to have human homolog(s).
This gene encodes a member of the potassium channel, voltage-gated,
shaker-related subfamily. This member contains six
membrane-spanning domains with a shaker-type repeat in the fourth
segment. It belongs to the delayed rectifier class, the function of
which could restore the resting membrane potential of beta cells
after depolarization and thereby contribute to the regulation of
insulin secretion. This gene is intronless, and the gene is
clustered with genes KCNA1 and KCNA6 on chromosome 12. [provided by
RefSeq].
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Wipff, J., et al. Arthritis Rheum. 62(10):3093-3100(2010)
- Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
- Dou, Y., et al. Am. J. Physiol., Cell Physiol. 298 (6), C1343-C1352 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This KCNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-536 amino acids from the C-terminal region of human KCNA5.
3741
Potassium voltage-gated channel subfamily A member 5
KCNA5
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
P22460
146345443
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Neuroscience
P22460
Optimal dilutions for each application to be determined by the researcher.