ProSci

GC Antibody

Product Code:
 
PSI-61-272
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: human plasma lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: human plasma lysate Lysates/proteins at 20 ug per lane.

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PSI-61-272-200ul200ul£626.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC
Application Note:
For WB starting dilution is: 1:2000
Background:
Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Background References:
  • Cooke N.E.,et al.J. Clin. Invest. 76:2420-2424(1985).
  • Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998(1985).
  • Braun A.,et al.Biochim. Biophys. Acta 1216:385-394(1993).
  • Witke W.F.,et al.Genomics 16:751-754(1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 442-473 amino acids from human GC.
NCBI Gene ID #:
2638
NCBI Official Name:
Vitamin D-binding protein
NCBI Official Symbol:
GC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P02774
Protein GI Number:
139641
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P02774
User NOte:
Optimal dilutions for each application to be determined by the researcher.