Further Information
GRB2-related adapter protein 2, Adapter protein GRID, GRB-2-like protein, GRB2L, GRBLG, GRBX, Grf40 adapter protein, Grf-40, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, P38, Protein GADS, SH3-SH2-SH3 adapter Mona, GRAP2, GADS, GRB2L, GRID
For WB starting dilution is: 1:1000
This gene encodes a member of the GRB2/Sem5/Drk family.
This member is an adaptor-like protein involved in
leukocyte-specific protein-tyrosine kinase signaling. Like its
related family member, GRB2-related adaptor protein (GRAP), this
protein contains an SH2 domain flanked by two SH3 domains. This
protein interacts with other proteins, such as GRB2-associated
binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2),
through its SH3 domains. Transcript variants utilizing alternative
polyA sites exist.
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Preisinger, C., et al. Cell. Signal. 22(5):848-856(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
9402
GRB2-related adapter protein 2
GRAP2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
38 kDa
O75791
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Signal Transduction
O75791
Optimal dilutions for each application to be determined by the researcher.