ProSci

PDGFC Antibody

Product Code:
 
PSI-59-045
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
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PDGFC antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in MDA-MB231 cell line lysates (35ug/lane).
PDGFC antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-59-045-400ul400ul£626.00
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This product comes from: United States.
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Further Information

Additional Names:
Platelet-derived growth factor C, PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, Platelet-derived growth factor C, latent form, PDGFC latent form, Platelet-derived growth factor C, receptor-binding form, PDGFC receptor-binding form, PDGFC, SCDGF
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Platelet-derived growth factor C (PDGFC) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFC seems to form only homodimers, where the dimers are connected by disulfide bonds. It differs from the platelet-derived growth factor alpha (PDGFA) and beta (PDGFB) in having an unusual N-terminal domain, the CUB domain.
Background References:
  • Fang, L., et al., Arterioscler. Thromb. Vasc. Biol. 24(4):787-792 (2004). Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003). Eitner, F., et al., J. Am. Soc. Nephrol. 14(5):1145-1153 (2003). Reigstad, L.J., et al., J. Biol. Chem. 278(19):17114-17120 (2003). Zwerner, J.P., et al., Oncogene 21(24):3847-3854 (2002).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Immunogen:
This PDGFC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human PDGFC.
NCBI Gene ID #:
56034
NCBI Official Name:
Platelet-derived growth factor C
NCBI Official Symbol:
PDGFC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9NRA1
Protein GI Number:
205830662
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q9NRA1
User NOte:
Optimal dilutions for each application to be determined by the researcher.