ProSci

L3MBTL2 Antibody

Product Code:
 
PSI-57-579
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).

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PSI-57-579-400ul400ul£626.00
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Further Information

Additional Names:
Lethal(3)malignant brain tumor-like protein 2, H-l(3)mbt-like protein 2, L(3)mbt-like protein 2, L3MBTL2
Application Note:
For WB starting dilution is: 1:1000
Background:
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Background References:
  • Guo, Y., et al. Nucleic Acids Res. 37(7):2204-2210(2009)
  • Lechtenberg, B.C., et al. Protein Sci. 18(3):657-661(2009)
  • Trojer, P., et al. Cell 129(5):915-928(2007)
  • Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This L3MBTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 627-656 amino acids from the C-terminal region of human L3MBTL2.
NCBI Gene ID #:
83746
NCBI Official Name:
Lethal(3)malignant brain tumor-like protein 2
NCBI Official Symbol:
L3MBTL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q969R5
Protein GI Number:
27734418
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q969R5
User NOte:
Optimal dilutions for each application to be determined by the researcher.