ProSci

GPSM1 Antibody

Product Code:
 
PSI-56-616
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 2
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
2 / 2
GPSM1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
GPSM1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-56-616-400ul400ul£626.00
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Further Information

Additional Names:
G-protein-signaling modulator 1, Activator of G-protein signaling 3, GPSM1, AGS3
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
G proteins propagate intracellular signals initiated by G protein-coupled receptors. GPSM1, a receptor-independent activator of G protein signaling, is one of several factors that influence the basal activity of G protein signaling systems (Pizzinat et al., 2001 [PubMed 11278352]).
Background References:
  • Oner, S.S., et al. J. Biol. Chem. 285(44):33949-33958(2010)
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Vural, A., et al. Mol. Cell. Biol. 30(6):1528-1540(2010)
  • Groves, B., et al. PLoS ONE(1), E8877 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GPSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-468 amino acids from the Central region of human GPSM1.
NCBI Gene ID #:
26086
NCBI Official Name:
G-protein-signaling modulator 1
NCBI Official Symbol:
GPSM1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
Q86YR5
Protein GI Number:
294862435
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
Q86YR5
User NOte:
Optimal dilutions for each application to be determined by the researcher.