ProSci

PGLYRP1 Antibody

Product Code:
 
PSI-60-003
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB468 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB468 cell line lysates (35ug/lane).

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PSI-60-003-400ul400ul£626.00
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Further Information

Additional Names:
Peptidoglycan recognition protein 1, Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP, TNFSF3L
Application Note:
For WB starting dilution is: 1:1000
Background:
PGLYRP1 is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Dukhanina, E.A., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):13963-13967(2009)
  • Rohatgi, A., et al. Atherosclerosis 203(2):569-575(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PGLYRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human PGLYRP1.
NCBI Gene ID #:
8993
NCBI Official Name:
Peptidoglycan recognition protein 1
NCBI Official Symbol:
PGLYRP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O75594
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology,Neuroscience
Swissprot #:
O75594
User NOte:
Optimal dilutions for each application to be determined by the researcher.