ProSci

CRX Antibody

Product Code:
 
PSI-61-066
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis of lysate from Y79 cell line, using CRX Antibody at 1:1000.
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Western blot analysis of lysate from Y79 cell line, using CRX Antibody at 1:1000.

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PSI-61-066-400ul400ul£626.00
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Further Information

Additional Names:
Cone-rod homeobox protein, CRX, CORD2
Application Note:
For WB starting dilution is: 1:1000
Background:
Binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, e.g. NRL and RX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.
Background References:
  • Freund C.L.,et al.Cell 91:543-553(1997).
  • Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
  • Grimwood J.,et al.Nature 428:529-535(2004).
  • Roni V.,et al.BMC Genomics 8:42-42(2007).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This CRX antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 294-297 amino acids from the C-terminal region of human CRX.
NCBI Gene ID #:
1406
NCBI Official Name:
Cone-rod homeobox protein
NCBI Official Symbol:
CRX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
O43186
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
O43186
User NOte:
Optimal dilutions for each application to be determined by the researcher.