ProSci

MMEL1 Antibody

Product Code:
 
PSI-60-895
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in human Uterus tissue lysates (35ug/lane).
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Western blot analysis in human Uterus tissue lysates (35ug/lane).

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PSI-60-895-400ul400ul£626.00
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Further Information

Additional Names:
Membrane metallo-endopeptidase-like 1, Membrane metallo-endopeptidase-like 2, NEP2(m), Neprilysin II, NEPII, Neprilysin-2, NEP2, NL2, Membrane metallo-endopeptidase-like 1, soluble form, Neprilysin-2 secreted, NEP2(s), MMEL1, MELL1, MMEL2, NEP2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart.
Background References:
  • van der Helm-van Mil, A.H., et al. Ann. Rheum. Dis. 69(9):1694-1696(2010)
  • Hirschfield, G.M., et al. Nat. Genet. 42(8):655-657(2010)
  • Stahl, E.A., et al. Nat. Genet. 42(6):508-514(2010)
  • Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human MMEL1.
NCBI Gene ID #:
79258
NCBI Official Name:
Membrane metallo-endopeptidase-like 1
NCBI Official Symbol:
MMEL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
89 kDa
Protein Accession #:
Q495T6
Protein GI Number:
114150028
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q495T6
User NOte:
Optimal dilutions for each application to be determined by the researcher.