ProSci

AATK Antibody

Product Code:
 
PSI-57-784
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lane 3: A549 whole cell lysates Lysates/proteins at 20 ug per lane.
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Western blot analysis in CEM cell line lysates (35ug/lane).
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lane 3: A549 whole cell lysates Lysates/proteins at 20 ug per lane.
Western blot analysis in CEM cell line lysates (35ug/lane).

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PSI-57-784-400ul400ul£626.00
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Further Information

Additional Names:
Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.
Background References:
  • Tomomura, M., et al. Neurobiology 148(2):510-521(2007)
  • Lee, S., et al. Oncol. Rep. 16(4):747-754(2006)
  • Honma, N., et al. Biochem. Biophys. Res. Commun. 310(2):398-404(2003)
  • Tomomura, M., et al. Brain Res. Mol. Brain Res. 112 (1-2), 103-112 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This AATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human AATK.
NCBI Gene ID #:
9625
NCBI Official Name:
Serine/threonine-protein kinase LMTK1
NCBI Official Symbol:
AATK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
145 kDa
Protein Accession #:
Q6ZMQ8
Protein GI Number:
114149222
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience,Signal Transduction
Swissprot #:
Q6ZMQ8
User NOte:
Optimal dilutions for each application to be determined by the researcher.