Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH, UGDH
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
The protein encoded by this gene converts UDP-glucose to
UDP-glucuronate and thereby participates in the biosynthesis of
glycosaminoglycans such as hyaluronan, chondroitin sulfate, and
heparan sulfate. These glycosylated compounds are common components
of the extracellular matrix and likely play roles in signal
transduction, cell migration, and cancer growth and metastasis. The
expression of this gene is up-regulated by transforming growth
factor beta and down-regulated by hypoxia. Alternative splicing
results in multiple transcript variants.
- Wang, T.P., et al. Exp. Cell Res. 316(17):2893-2902(2010)
- Hodgkinson, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 107(19):8695-8700(2010)
- Huang, D., et al. Int. J. Cancer 126(2):315-327(2010)
- Lee, H.S., et al. Arch. Biochem. Biophys. 486(1):35-43(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This UGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human UGDH.
7358
UDP-glucose 6-dehydrogenase
UGDH
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
O60701
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Obesity,Signal Transduction
O60701
Optimal dilutions for each application to be determined by the researcher.