ProSci

MARH3 Antibody

Product Code:
 
PSI-59-505
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

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PSI-59-505-400ul400ul£626.00
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Further Information

Additional Names:
E3 ubiquitin-protein ligase MARCH3, 632-, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, MARCH-III, RING finger protein 173, MARCH3, RNF173
Application Note:
For WB starting dilution is: 1:1000
Background:
MARCH3 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH3 appears to function in the endosomal recycling pathway (Fukuda et al., 2006 [PubMed 16428329]).
Background References:
  • Fukuda, H., et al. J. Biochem. 139(1):137-145(2006)
  • Bartee, E., et al. J. Virol. 78(3):1109-1120(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This MARH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-251 amino acids from the C-terminal region of human MARH3.
NCBI Gene ID #:
115123
NCBI Official Name:
E3 ubiquitin-protein ligase MARCH3
NCBI Official Symbol:
Mar-03
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
Q86UD3
Protein GI Number:
59798460
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q86UD3
User NOte:
Optimal dilutions for each application to be determined by the researcher.