Further Information
Serine/threonine-protein kinase 4, Mammalian STE20-like protein kinase 1, MST-1, STE20-like kinase MST1, Serine/threonine-protein kinase Krs-2, Serine/threonine-protein kinase 4 37kDa subunit, MST1/N, Serine/threonine-protein kinase 4 18kDa subunit, MST1/C, STK4, KRS2, MST1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.
- Cheung, W.L., et al., Cell 113(4):507-517 (2003).
- Lin, Y., et al., J. Biol. Chem. 277(50):47991-48001 (2002).
- De Souza, P.M., et al., Blood 99(9):3432-3438 (2002).
- Ura, S., et al., Proc. Natl. Acad. Sci. U.S.A. 98(18):10148-10153 (2001).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine
This MST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human MST1.
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Serine/threonine-protein kinase 4
STK4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Q13043
13124559
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cell Cycle,Signal Transduction
Q13043
Optimal dilutions for each application to be determined by the researcher.