ProSci

FBXO32 Antibody

Product Code:
 
PSI-61-173
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-61-173-200ul200ul£626.00
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Further Information

Additional Names:
F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, FBXO32
Application Note:
For WB starting dilution is: 1:2000
Background:
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Background References:
  • Bodine S.C.,et al.Science 294:1704-1708(2001).
  • Sivertsen E.A.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
  • Pescatori M.,et al.Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
  • Ota T.,et al.Nat. Genet. 36:40-45(2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This FBXO32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 17-49 amino acids from human FBXO32.
NCBI Gene ID #:
114907
NCBI Official Name:
F-box only protein 32
NCBI Official Symbol:
FBXO32
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q969P5
Protein GI Number:
20177894
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Stem Cell
Swissprot #:
Q969P5
User NOte:
Optimal dilutions for each application to be determined by the researcher.