Further Information
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
For WB starting dilution is: 1:1000
The protein encoded by this gene is a member of the folate
receptor (FOLR) family, and these genes exist in a cluster on
chromosome 11. Members of this gene family have a high affinity for
folic acid and for several reduced folic acid derivatives, and they
mediate delivery of 5-methyltetrahydrofolate to the interior of
cells. This protein has a 68% and 79% sequence homology with the
FOLR1 and FOLR3 proteins, respectively. Although this protein was
originally thought to be specific to placenta, it can also exist in
other tissues, and it may play a role in the transport of
methotrexate in synovial macrophages in rheumatoid arthritis
patients. Multiple transcript variants that encode the same protein
have been found for this gene.
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse
This FOLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human FOLR2.
2350
Folate receptor beta
FOLR2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
P14207
116241366
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Obesity,Signal Transduction
P14207
Optimal dilutions for each application to be determined by the researcher.