ProSci

MEFV Antibody

Product Code:
 
PSI-60-653
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.

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PSI-60-653-400ul400ul£626.00
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Further Information

Additional Names:
Pyrin, Marenostrin, MEFV, MEF
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.
Background References:
  • Cosan, F., et al. Arthritis Rheum. 62(11):3232-3236(2010)
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • He, X., et al. Pediatr. Nephrol. 25(10):2077-2082(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MEFV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418-445 amino acids from the Central region of human MEFV.
NCBI Gene ID #:
4210
NCBI Official Name:
Pyrin
NCBI Official Symbol:
MEFV
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
O15553
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
O15553
User NOte:
Optimal dilutions for each application to be determined by the researcher.