ProSci

FCGR2A Antibody

Product Code:
 
PSI-57-224
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis of FCGR2A using rabbit polyclonal FCGR2A Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCGR2A gene.
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis of FCGR2A using rabbit polyclonal FCGR2A Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCGR2A gene.

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PSI-57-224-400ul400ul£626.00
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Further Information

Additional Names:
Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, CDw32, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, CD32, FCGR2A, CD32, FCG2, FCGR2A1, IGFR2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Background References:
  • Dornan, D., et al. Blood 116(20):4212-4222(2010)
  • Zhang, C.Y., et al. J. Biol. Chem. 285(44):34250-34258(2010)
  • Iwasaki, M., et al. Breast Cancer Res. Treat. (2010) In press :
  • Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FCGR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the C-terminal region of human FCGR2A.
NCBI Gene ID #:
2212
NCBI Official Name:
Low affinity immunoglobulin gamma Fc region receptor II-a
NCBI Official Symbol:
FCGR2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
P12318
Protein GI Number:
160332371
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
P12318
User NOte:
Optimal dilutions for each application to be determined by the researcher.