Further Information
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, IL1R2, IL1RB
For WB starting dilution is: 1:1000
The protein encoded by this gene is a cytokine receptor
that belongs to the interleukin 1 receptor family. This protein
binds interleukin alpha (IL1A), interleukin beta (IL1B), and
interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy
receptor that inhibits the activity of its ligands. Interleukin 4
(IL4) is reported to antagonize the activity of interleukin 1 by
inducing the expression and release of this cytokine. This gene and
three other genes form a cytokine receptor gene cluster on
chromosome 2q12. Two alternatively spliced transcript variants
encoding the same protein have been reported.
- Giroux, S., et al. Bone 47(5):975-981(2010)
- Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Chen, C., et al. Rheumatol. Int. (2010) In press :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This IL1R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the Central region of human IL1R2.
7850
Interleukin-1 receptor type 2
IL1R2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
P27930
124310
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Signal Transduction
P27930
Optimal dilutions for each application to be determined by the researcher.