ProSci

TRIM22 Antibody

Product Code:
 
PSI-60-591
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in A549 cell line lysates (35ug/lane).
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Western blot analysis in A549 cell line lysates (35ug/lane).

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PSI-60-591-400ul400ul£626.00
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Further Information

Additional Names:
E3 ubiquitin-protein ligase TRIM22, 632-, 50 kDa-stimulated trans-acting factor, RING finger protein 94, Staf-50, Tripartite motif-containing protein 22, TRIM22, RNF94, STAF50
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.
Background References:
  • Kajaste-Rudnitski, A., et al. Amino Acids 39(1):1-9(2010)
  • Petersson, J., et al. Exp. Cell Res. 316(4):568-579(2010)
  • Ovsyannikova, I.G., et al. Hum. Genet. 127(2):207-221(2010)
  • Ovsyannikova, I.G., et al. J. Infect. Dis. 201(2):207-213(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRIM22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM22.
NCBI Gene ID #:
10346
NCBI Official Name:
E3 ubiquitin-protein ligase TRIM22
NCBI Official Symbol:
TRIM22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q8IYM9
Protein GI Number:
47606181
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q8IYM9
User NOte:
Optimal dilutions for each application to be determined by the researcher.