Further Information
Macrophage erythroblast attacher, Cell proliferation-inducing gene 5 protein, Erythroblast macrophage protein, Human lung cancer oncogene 10 protein, HLC-10, MAEA, EMP
For WB starting dilution is: 1:1000
This gene product mediates the attachment of erythroblasts
to macrophages. This attachment promotes terminal maturation and
enucleation of erythroblasts, presumably by suppressing apoptosis.
This protein is an integral membrane protein with the N-terminus on
the extracellular side and the C-terminus on the cytoplasmic side
of the cell. Two immunologically related isoforms of erythroblast
macrophage protein with apparent molecular weights of 33 kD and 36
kD were detected in macrophage membranes; this gene encodes the
larger isoform. Multiple alternatively spliced transcript variants
encoding distinct isoforms have been found for this gene, but the
biological validity of some variants has not been determined.
- Kobayashi, N., et al. Gene 396(2):236-247(2007)
- Bala, S., et al. Biochem. Biophys. Res. Commun. 342(4):1040-1048(2006)
- Hanspal, M., et al. Blood 92(8):2940-2950(1998)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Monkey, Mouse, Rat, Xenopus
This MAEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-42 amino acids from the N-terminal region of human MAEA.
10296
Macrophage erythroblast attacher
MAEA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Q7L5Y9
74754297
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Signal Transduction
Q7L5Y9
Optimal dilutions for each application to be determined by the researcher.