Further Information
Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, CD258, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form, TNFSF14, HVEML, LIGHT
For WB starting dilution is: 1:1000
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) ligand family. This protein is a ligand for
TNFRSF14, which is a member of the tumor necrosis factor receptor
superfamily, and which is also known as a herpesvirus entry
mediator (HVEM). This protein may function as a costimulatory
factor for the activation of lymphoid cells and as a deterrent to
infection by herpesvirus. This protein has been shown to stimulate
the proliferation of T cells, and trigger apoptosis of various
tumor cells. This protein is also reported to prevent tumor
necrosis factor alpha mediated apoptosis in primary hepatocyte. Two
alternatively spliced transcript variant encoding distinct isoforms
have been reported.
- Stiles, K.M., et al. J. Virol. 84(22):11646-11660(2010)
- Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This TNFSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the Central region of human TNFSF14.
8740
Tumor necrosis factor ligand superfamily member 14
TNFSF14
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
O43557
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology,Signal Transduction
O43557
Optimal dilutions for each application to be determined by the researcher.