Further Information
Potassium voltage-gated channel subfamily D member 3, Voltage-gated potassium channel subunit Kv43, KCND3
For WB starting dilution is: 1:1000
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shal-related subfamily, members of which form
voltage-activated A-type potassium ion channels and are prominent
in the repolarization phase of the action potential. This member
includes two isoforms with different sizes, which are encoded by
alternatively spliced transcript variants of this gene. [provided
by RefSeq].
- Lundby, A., et al. Br. J. Pharmacol. 160(8):2028-2044(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Liang, P., et al. Biophys. J. 98(12):2867-2876(2010)
- Cotella, D., et al. Pflugers Arch. 460(1):87-97(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This KCND3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human KCND3.
3752
Potassium voltage-gated channel subfamily D member 3
KCND3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
73 kDa
Q9UK17
92090984
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience
Q9UK17
Optimal dilutions for each application to be determined by the researcher.