Further Information
Beta-crystallin B3, Beta-B3 crystallin, Beta-crystallin B3, N-terminally processed, CRYBB3, CRYB3
For WB starting dilution is: 1:1000
Crystallins are separated into two classes:
taxon-specific, or enzyme, and ubiquitous. The latter class
constitutes the major proteins of vertebrate eye lens and maintains
the transparency and refractive index of the lens. Since lens
central fiber cells lose their nuclei during development, these
crystallins are made and then retained throughout life, making them
extremely stable proteins. Mammalian lens crystallins are divided
into alpha, beta, and gamma families; beta and gamma crystallins
are also considered as a superfamily. Alpha and beta families are
further divided into acidic and basic groups. Seven protein regions
exist in crystallins: four homologous motifs, a connecting peptide,
and N- and C-terminal extensions. Beta-crystallins, the most
heterogeneous, differ by the presence of the C-terminal extension
(present in the basic group, none in the acidic group).
Beta-crystallins form aggregates of different sizes and are able to
self-associate to form dimers or to form heterodimers with other
beta-crystallins. This gene, a beta basic group member, is part of
a gene cluster with beta-A4, beta-B1, and beta-B2. [provided by
RefSeq].
- Muller, C., et al. Anim. Genet. 39(1):87-88(2008)
- Wu, C., et al. Proteomics 7(11):1775-1785(2007)
- Riazuddin, S.A., et al. Invest. Ophthalmol. Vis. Sci. 46(6):2100-2106(2005)
- Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This CRYBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human CRYBB3.
1417
Beta-crystallin B3
CRYBB3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
P26998
311033476
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience
P26998
Optimal dilutions for each application to be determined by the researcher.