Further Information
Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein 20, DEAD box protein DP 103, Gemin-3, DDX20, DP103, GEMIN3
For WB starting dilution is: 1:1000
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
which has an ATPase activity and is a component of the survival of
motor neurons (SMN) complex. This protein interacts directly with
SMN, the spinal muscular atrophy gene product, and may play a
catalytic role in the function of the SMN complex on RNPs.
- Todd, A.G., et al. J. Mol. Biol. 401(5):681-689(2010)
- Sun, X., et al. Cell Stress Chaperones 15(5):567-582(2010)
- Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
- Boni, V., et al. Pharmacogenomics J. (2010) In press :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This DDX20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-741 amino acids from the C-terminal region of human DDX20.
11218
Probable ATP-dependent RNA helicase DDX20
DDX20
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
92 kDa
Q9UHI6
12643886
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience
Q9UHI6
Optimal dilutions for each application to be determined by the researcher.